MDMA, NMDA, NDMA (confused yet?)

1) MDMA ( methylenedioxy-methylamphetamine) : a hallucinogen also called Molly and Ecstasy.  Has potential beneficial use for severe mental health issues.  See this New York Times article:
https://www.nytimes.com/2021/05/03/health/mdma-approval.html?smid=url-share

2) NMDA (N-Methyl-d-aspartic acid or N-Methyl-d-aspartate) (and the associated NMDA RECEPTORS): what my ketamine clinic tries to manipulate in order to help patients with treatment resistant depression, patients with significant anxiety, patients with PTSD, and patients with neuropathic pain. NMDA mimics the excitatory neurotransmitter glutamate by binding to the NMDA RECEPTOR. KETAMINE (a cousin of PCP, Angel Dust) actually blocks the NMDA from binding to this NMDA RECEPTOR ( ie. blocks the effect of NMDA).

3) NDMA (N-nitrosodimethylamine): a yellow oil which is highly toxic to the liver and causes cancer. In the last few years this carcinogen has been found in production facilities and in these products: Zantac (stomach acid suppression), Diovan (blood pressure medicine), Metformin ER (diabetes medicine).

Charles Tadros, M.D.

November 10, 2021

Saint Louis, Missouri

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